本ページの概要
本ページは「うつ病・気分症群」について、患者調査・制度・文献・可視化リソースを統合してご紹介します。 内容は月次の自動更新で随時追記されます。
患者調査(時系列)
出典: 厚生労働省 患者調査
| 年 | 総患者数_千人 | うつ病等_千人 | 双極性障害_千人 | 入院患者数_千人 | 外来患者数_千人 | 出典 |
|---|---|---|---|---|---|---|
| 1999 | 441.0 | 298.0 | 71.0 | 96.0 | 345.0 | 患者調査 |
| 2002 | 714.0 | 491.0 | 109.0 | 102.0 | 612.0 | 患者調査 |
| 2005 | 922.0 | 637.0 | 138.0 | 105.0 | 817.0 | 患者調査 |
| 2008 | 1040.0 | 728.0 | 161.0 | 106.0 | 934.0 | 患者調査 |
| 2011 | 958.0 | 670.0 | 148.0 | 98.0 | 860.0 | 患者調査(東日本大震災影響で一時減) |
| 2014 | 1116.0 | 788.0 | 166.0 | 100.0 | 1016.0 | 患者調査 |
| 2017 | 1276.0 | 933.0 | 185.0 | 97.0 | 1179.0 | 患者調査 |
| 2020 | 1722.0 | 1275.0 | 217.0 | 95.0 | 1627.0 | 患者調査(コロナ禍急増) |
| 2023 | 2000.0 | 1490.0 | 252.0 | 94.0 | 1906.0 | 患者調査(推計) |
国際比較
出典: OECD Health Statistics ほか
| 国 | 12ヶ月有病率(%) | 生涯有病率(%) | うつ病入院率_人口10万人あたり | 抗うつ薬処方率(%) | 出典 |
|---|---|---|---|---|---|
| 日本 | 2.2 | 6.7 | 14.0 | 9.5 | 川上ら2006・患者調査2020 |
| アメリカ | 8.3 | 17.1 | 35.0 | 18.4 | NSDUH2020 |
| ドイツ | 5.6 | 13.0 | — | 13.5 | ESEMeD |
| フランス | 4.7 | 10.0 | — | 18.2 | ESEMeD |
| イギリス | 5.0 | 12.0 | — | 16.5 | NHS2021 |
| 韓国 | 2.5 | 5.7 | — | — | KNHANES2020 |
| 世界平均 | 4.4 | — | — | — | WHO GBD2019 |
制度変遷メモ
うつ病・気分症群 診療体制・政策変遷メモ
主要制度転換点
1999年 — パキシル(パロキセチン)承認
- 日本初のSSRI(選択的セロトニン再取込み阻害薬)承認
- うつ病の診断・治療が急速に普及
- 患者数は1999年→2002年でほぼ倍増(44万→71万人)
2000年代前半 — 「うつは心の風邪」キャンペーン
- 製薬会社主導のメディア啓発
- 受診行動の大幅な変化(中等・軽症うつの受診増)
- 診断の裾野が拡大(DSM-IV基準の普及)
2006年 — ジェイゾロフト(セルトラリン)等の追加承認
- 複数のSSRI/SNRIが競合参入
- うつ病治療薬市場が急拡大
2009〜2010年 — 産業メンタルヘルス対策強化
- 自殺対策基本法(2006)→自殺総合対策大綱(2007)
- メンタルヘルス不調による休職者増加への対応
- 復職支援プログラム(リワーク)の普及
2011年 — 東日本大震災
- 被災地でのPTSD・うつ病急増
- こころのケアチーム派遣(DPAT前身)
- 一時的に患者数統計が乱れ(2011年調査:前回比減)
2014〜 — ストレスチェック義務化検討→施行(2015年)
- 50人以上事業所でストレスチェック義務化
- 職域でのうつ病早期発見・予防体制の整備
2015年 — レクサプロ(エスシタロプラム)普及
- 忍容性が高く汎用的なSSRIとして広がる
- 軽症うつへの投与が一般化
2020〜 — COVID-19パンデミック
- 患者数が2020年で前回比35%以上増加
- 孤独・孤立、失業、学業困難によるうつ病急増
- オンライン診療の普及でアクセスが改善
2023〜 — 現在
- 外来患者数200万人超(推計)
- 「隠れうつ」「マイクロうつ」等の概念の普及
- 精神科・心療内科の需要逼迫、予約待ち延長
診療体制上の課題
| 課題 | 状況 |
|---|---|
| 過少診断 vs 過剰診断 | 12ヶ月有病率の低さ(2.2%)と患者数急増の乖離 |
| 精神科・心療内科の過負荷 | 外来待機延長、1診療あたり時間が短縮 |
| 休職・復職支援 | リワークプログラムの保険適用外、企業格差 |
| 自殺との関連 | うつ病は自殺の最大危険因子(自殺者の60-90%にうつ) |
| 薬物療法偏重 | 認知行動療法等の心理療法は提供体制が不十分 |
関連文献
出典: PubMed 等。最新登録順。 全 113 件中、最新 15 件を表示しています。
- Polukchi TV. Prevalence and severity of depression in patients with chronic viral hepatitis in Kazakhstan. Psychiatrike = Psychiatriki (2026). PMID: 40789194 DOI
- Li S, Ma Y, Wu T, Chen J, Zhu Z, et al. Prevalence and associated factors of EPDS-defined depressive symptoms in fathers of preterm infants admitted to the NICU: a cross-sectional study. BMC pregnancy and childbirth (2026). PMID: 42271304 DOI
- Yuan G, Pu Y, Xiao L, Chen N, Wang Z, et al. Trends in obesity prevalence among adults with depression in the United States, 2005 to 2023. BMC psychiatry (2026). PMID: 42298483 DOI
- Drzymała S, Blask-Osipa A, Szczepańska-Alvarez A, Markowska H, Dobrzyńska M, et al. Anxiety-Depressive Disorders in 200 Patients with Post-COVID-19 Syndrome: Prevalence and Predictors from a Cross-Sectional Study. Medicina (Kaunas, Lithuania) (2026). PMID: 42512777 DOI
- Ahmad A, Hassan Rizvi A, Uzair M, Bashir H, Amin M. Prevalence of internet addiction and its relation with depression, anxiety and stress in medical students of Pakistan. Psychology, health & medicine (2026). PMID: 40876826 DOI
- Yavuzlar Civan H, Berkol TD. ADHD Comorbidity in Women with Depression and Anxiety: Prevalence, Clinical Features and Hyperfocus Dynamics. International journal of psychiatry in medicine (2026). PMID: 40934870 DOI
- Mariani LL, Dano B, Houot M, Mangone G, Pico F, et al. Risk of Falls and Need of Walking Aid in Parkinson's Disease: Incidence and Impact of Comorbidities. Movement disorders clinical practice (2026). PMID: 41612959 DOI
- Astridge A, Copas C, Hannon O, Martins BD, Knight JM, et al. Prevalence and predictors of post-traumatic stress disorder, depression, and anxiety among community-dwelling women victim-survivors of intimate partner violence. Social psychiatry and psychiatric epidemiology (2026). PMID: 41838071 DOI
- Zhitnik E, Britt T, Bertone-Johnson E, Mackie TI, Hartmann-Boyce J. Prevalence, Risk Factors, and Treatments for Suicidality in People Living with Premenstrual Dysphoric Disorder (PMDD): A Systematic Review. Administration and policy in mental health (2026). PMID: 42045645 DOI
- Qutishat M, Al Alawi M, Al-Hadidi M, Sharour LA, Sinawi HA, et al. Prevalence, Predictors, and Challenges in the Management of Depression Among Patients on Hemodialysis in the Arab Countries: A Systematic Review. Hemodialysis international. International Symposium on Home Hemodialysis (2026). PMID: 42093361 DOI
- Almulla AA, Khasawneh MAS. Exploring the Prevalence and Key Predictors of Probable Depression Among Parents and Primary Caregivers of Children and Adolescents With Specific Learning Disorders in the Kingdom of Saudi Arabia: A Cross-Sectional Explainable Machine-Learning Study. Clinical psychology & psychotherapy (2026). PMID: 42490731 DOI
- Alexatou O, Papadopoulou SK, Angelakou EP, Migdanis A, Louka A, et al. Emotional Eating and Its Associations with the Prevalence of Depression and Anxiety Symptoms in University Students: A Cross-Sectional Study. Medical sciences (Basel, Switzerland) (2026). PMID: 42506345 DOI
- Montgomery BW, Elkasabi M, Brannock MD, Marcial L, Huda A, et al. Assessing the generalizability of prevalence estimates from the All of Us Research Program. American journal of epidemiology (2026). PMID: 41536210 DOI
- Li T, He J, Mao Y, Li H. Prevalence of depression among rural older adults in Asia: a meta-analysis of observational studies. Frontiers in public health (2026). PMID: 42487818 DOI
- Al Hattawi KS, Rahman MM, Alam E, Shobuj IA, Hossain MT. Prevalence and associated factors of depression, anxiety, and stress among flood-affected women in Bangladesh: a case study following 2024 flash flood. Frontiers in public health (2026). PMID: 42494895 DOI
過去の文献 98 件を表示
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- Liu Y. The impact of social participation trajectories on depression incidence among Chinese older adults. BMC geriatrics (2026). PMID: 42477547 DOI
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- Bayas MA, Auerbach J, Diekamp B, Fomenko M, Baune BT, et al. Population-based prevalence and pharmacotherapy sequences of treatment resistant depression in Germany. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology (2026). PMID: 42119282 DOI
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- He Y, Xu T, Zhou X, Chai X, Tan X, et al. Prevalence and psychosocial correlates of depression, anxiety and stress among caregivers of children with childhood-onset systemic lupus erythematosus in China: a cross-sectional study. BMJ open (2026). PMID: 42229969 DOI
- Pan Y, Musselman DL, Mithani Z, Tong W, Lu Y, et al. HIV, nephrotoxic medications, and chronic kidney disease: Prevalence, risk factors, and mediation analyses among people with and without HIV enrolled in the Multicenter AIDS Cohort Study (MACS)/ Women's Interagency HIV Study (WIHS) combined cohort study. PloS one (2026). PMID: 42268922 DOI
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- Sirotich E, Lowry W, Wang SY, Jurgens M, Cohen JM. Incidence of depression in patients with psoriasis and psoriatic arthritis treated with biologic therapy: Protocol for a systematic review and meta-analysis. PloS one (2026). PMID: 42371910 DOI
- Oi I, Ito I, Hamao N, Shirata M, Nishioka K, et al. High prevalence of depressive symptoms and its impact on quality of life in patients with Mycobacterium avium complex lung disease. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (2026). PMID: 42106070 DOI
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- Zheng MR, Feng Y, Zhang Q, Sha S, Su Z, et al. Gender Differences in the Prevalence and Correlates of Post-Stroke Depression Among Older Stroke Survivors: Findings From a National Survey in China. Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists (2026). PMID: 42009559 DOI
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- Li ZY, Wang J, Yang JS, Xu X, Wang F, et al. Study protocol for the effect of intraoperative subanaesthetic dose esketamine on the incidence of postoperative depressive symptoms in patients with breast cancer: a multicentre, prospective, randomised controlled trial. BMJ open (2026). PMID: 42192642 DOI
- Kwarteng MA, Ogiemudia OM, Ekpenyong BN, Amaechi OU, Ogbonna G, et al. Prevalence and severity of anxiety, depression, and stress among optometry students in Nigeria: A cross-sectional study. PloS one (2026). PMID: 42189788 DOI
- Shaheen M, Amasha FA, Riad N, Ail OM, Morshed MI, et al. Prevalence of obsessive-compulsive symptoms and associations with psychological distress and quality of life among medical students in Egypt: a multicentre cross-sectional study. BMJ open (2026). PMID: 42203267 DOI
- El Khoury J, Bader E, Hallal M, Salameh P, Abed El Sater R, et al. Body dysmorphic disorder in Lebanese dermatology patients: prevalence and correlates of depression, anxiety, stress, and trauma in a multitraumatized population. European journal of psychotraumatology (2026). PMID: 42186903 DOI
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- Qing H, Ye L. Prevalence and Influencing Factors of Anxiety and Depression in Patients With Breast Cancer: A Meta-Analysis. Actas espanolas de psiquiatria (2026). PMID: 42023446 DOI
- Nguyen HP, Nguyen TTP, Nguyen NQ, Van Bui T, Le HA, et al. Prevalence of depression, anxiety and stress and associated workplace stressors among healthcare workers in a tertiary hospital in Vietnam: A cross-sectional study. PloS one (2026). PMID: 42008457 DOI
- Cheng R, Zhu W, Jiang S, Yang Z. Subthreshold depression prevalence and influencing factors among nursing students in vocational schools: A cross-sectional study. PloS one (2026). PMID: 42008490 DOI
- Tshomo T, Wongnuch P, Srichan P. Prevalence of and factors associated with depressive symptoms among the working population in Thimphu, Bhutan: A cross-sectional study. PloS one (2026). PMID: 42013137 DOI
- Hine BA, Harman JJ, Leder-Elder S, Bates EA. Prevalence and impact of parental alienating behaviors (PABs) in adults aged 18-25 in the United Kingdom. Frontiers in public health (2026). PMID: 42110299 DOI
- Tong L, Fan J, Wang X. Incidence of anxiety and depression in epilepsy patients and its correlation with disease control: A retrospective study. Medicine (2026). PMID: 42071840 DOI
- Necho M, Shegaw M, Anbesaw T, Birru N, Ayano G, et al. Prevalence of perinatal depression in Ethiopia: An umbrella review of systematic review and meta-analysis studies. PloS one (2026). PMID: 42044134 DOI
- de Araujo Lima D, de Paiva VA, de Souza Ribeiro AL, Zamboti CL. Sleep quality in pregnant women with lumbopelvic pain: prevalence of clinically significant sleep disturbance and comparison in clinical outcomes between pregnant women with and without clinically significant sleep disturbance. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine (2026). PMID: 42045728 DOI
- Ferreira RJDS, Monteiro CN, Dias DA, Rosa MRDD, Mondelli MFCG. Prevalence and characterization of tinnitus in patients with mental disorders in the context of primary health care. CoDAS (2026). PMID: 42054186 DOI
- Thapa K, Bhusal R, Mishra DKK, Shakya P. Prevalence and correlates of anxiety and depression among LGBT individuals in Nepal: a cross-sectional study. BMJ open (2026). PMID: 42049292 DOI
- Bojorquez I, Ibarra-González I, Pérez-Duperou G, Hernández C. Prevalence and Associated Factors of Mental Health Problems Among Internally Displaced Persons In-Transit in Mexico. The International journal of social psychiatry (2026). PMID: 41054324 DOI
- Gui Z, Chen P, Sha S, Zhang L, Su Z, et al. Gender Differences in Depression Prevalence, Influencing Factors, Life Satisfaction, and Network Structure Among Middle-Aged and Older Adults in China: A National Survey. The International journal of social psychiatry (2026). PMID: 41104581 DOI
- Braciszewski JM, Elmali M, Llamocca EN, Vanderziel AM, Cameron-Carter H, Loree AM. Prevalence and Mental Health Correlates of Electronic Cigarette Use Among Pediatric Primary Care Patients. Clinical pediatrics (2026). PMID: 41461569 DOI
- Beckodro CK, Nsitou B, Edwards Q, Asifat O, Sullivan KL, Cowan LT. Electronic cigarette use and postpartum depression prevalence: The pregnancy risk assessment monitoring system (PRAMS). Journal of affective disorders (2026). PMID: 41506386 DOI
- Lehmann G, Ehrmann D, Olesen B, Priesterroth LS, Kulzer B, et al. Uncovering distinct predictors of diabetes distress and depressive symptoms in a longitudinal survival analysis of incidence and remission: indication for diverging aetiological paths. Diabetologia (2026). PMID: 41572009 DOI
- Cénat JM, Farahi SMMM, Dalexis RD, Jean L, Lafleur N, et al. Severe depression among Haiti's internally displaced populations: Prevalence and correlates in the context of gang violence. Psychiatry research (2026). PMID: 41687330 DOI
- Xu T, Chen Y, Shen Q, Dai S, Yan H, Ren J. A systematic review and meta-analysis of anxiety and depression in children and adolescents with inflammatory bowel disease: Prevalence and association. Journal of psychiatric research (2026). PMID: 41687568 DOI
- Thiele T, Ahrenstorf G, Witte T, Kahl KG, Hirsch S. Prevalence and recognition gap of depressive and anxiety symptoms in patients with inflammatory-rheumatic diseases - a single center experience. Journal of psychiatric research (2026). PMID: 41719638 DOI
- Liu X, Xu A, Zhu Y, Pan Q, Wang H, Zhang G. Prevalence and risk factors associated with anxiety and depression in patients with acute ischemic stroke who receive mechanical thrombectomy. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association (2026). PMID: 41831582 DOI
- Pavlović Z, Stevanović M, Krstić A, Ivković I, Vujčić M, et al. Vitamin D Deficiency in Bipolar Disorder: Prevalence, Sociodemographic and Clinical Characteristics. Human psychopharmacology (2026). PMID: 42063248 DOI
- Lu J, Li K, Wu S, Feng H, Dong Z, Zheng Z. The impact of different combinations of body mass index and depressive status on the incidence of sarcopenia in middle-aged and older adults ≥45 years: A retrospective cohort study based on CHARLS follow-up data from 2011 to 2015. Medicine (2026). PMID: 42116348 DOI
- Wang F, Lai X, Zhou S, Lin J, Xin H, et al. Olanzapine-Associated Hepatotoxicity in Bipolar Disorder: A Multicenter Real-World Study of Prevalence, Risk Factors, and Outcomes. Drug design, development and therapy (2026). PMID: 42130898 DOI
- Romeu D, Jadhakhan F, Taylor AK, Lindner OC, Blakemore A, Guthrie E. Prevalence of anxiety and depression in adults who are high users of healthcare services and magnitude of associated costs: a systematic review. BMJ open (2026). PMID: 42128508 DOI
- Shin D, Ham BJ, Kim KH. Affective morbidity after cancer diagnosis: Nationwide incidence and pharmacotherapy patterns across five major cancer types. Journal of affective disorders (2026). PMID: 41619608 DOI
- Mirchandani S, Tan MP, Morgan K. Prevalence and Characteristics of Depression, Anxiety and Stress Among Older Persons in Malaysia during the COVID-19 Pandemic. Journal of cross-cultural gerontology (2026). PMID: 42144482 DOI
- Liao T, Gan Y, Liu L, Tang M, Gan L, Li G. Prevalence and Associated Factors of Frailty in Middle-Aged and Elderly Patients with Atrial Fibrillation: An Exploratory Machine Learning Analysis. Clinical interventions in aging (2026). PMID: 42179963 DOI
- Sarkar AA, Alam MF, Ahmed HU, Alam MT, Khan NM. Prevalence, symptom profile, associated factors, and treatment gap of depressive disorders among adults: Findings from a nationwide household survey in Bangladesh. Journal of affective disorders (2026). PMID: 41672149 DOI
- Verbist IL, Lorimer B. Physical long-term conditions and psychological treatment outcomes in NHS Talking Therapies: Prevalence, impact, and moderators. The British journal of clinical psychology (2026). PMID: 41673545 DOI
- Smith M, Koons NJ, Callihan P, Guo N, Simard JF, et al. Prevalence of and Risk Factors for Postpartum Anxiety in a U.S. Cohort With Commercial Insurance. Obstetrics and gynecology (2026). PMID: 41747270 DOI
- de Aguiar KR, Zimmer C, Kampmann L, Caobelli ACSL, Chagas V, et al. Prevalence and clinical correlates of cocaine use disorder among patients diagnosed with bipolar disorder: A systematic review, meta-analysis, and meta-regression. Neuroscience and biobehavioral reviews (2026). PMID: 41833851 DOI
- Feng S, Liu L, Xiao G, Zhang Y, Zhou M, et al. Reassessing the burden of perinatal depression: A systematic review and meta-analysis on the prevalence and risk factors of perinatal depressive symptom trajectories. Midwifery (2026). PMID: 41856019 DOI
- Hadj-Youssef S, Civita A, Chartrand E, Malboeuf-Hurtubise C, Fuoco J, et al. Prevalence and mental health correlates of non-suicidal self-injury in elementary school children. Psychiatry research (2026). PMID: 41865642 DOI
- Halstead S, Arnautovska U, Kisely S, Siskind D, Warren N. Comparative incidence rates of physical multimorbidity in a psychiatric inpatient population among people with and without severe mental illness: A retrospective cohort study. The Australian and New Zealand journal of psychiatry (2026). PMID: 41877559 DOI
- Zhou L, Guan M, Zhang B, Zhao C, Sun Z, et al. Depression in Parkinson's disease: prevalence and impact on oculomotor features. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology (2026). PMID: 41895089 DOI
- Ferrari AJ, Miller PA, Shadid J, Herrera AM, Ahmed SM, et al. The global prevalence of major depressive disorder during the peripartum period: a systematic review and meta-regression. The lancet. Psychiatry (2026). PMID: 42070579 DOI
- Cham CQ, Ganapathy SS, Siau CS, Yahya N, Chan CMH, et al. Prevalence and factors associated with suicidal ideation based on the Malaysia National Health and Morbidity Survey: A machine learning analysis. Journal of affective disorders (2026). PMID: 41692050 DOI
- Williams HG, Jones ES, Roberts R, Woodman T, Peirce N. Prevalence of clinically significant symptoms of anxiety, depression and disordered eating in elite female athletes: A systematic review and meta-analysis. Psychology of sport and exercise (2026). PMID: 41713823 DOI
- Andrew Yockey R, Apu A, Grigsby T, Bleasdale J, Mattingly D, Hoopsick R. Decreasing prevalence in youth depressive episodes: Evidence from the 2021-2024 national survey on drug use and health. Journal of psychiatric research (2026). PMID: 41911630 DOI
- Chen M, Li M, Wan D, Zha J. Global, regional, and national burden of depressive disorders in older adults from 1990 to 2021, with projections of prevalence to 2050: a trend analysis for the Global Burden of Disease Study 2021. Journal of affective disorders (2026). PMID: 41780694 DOI
- Sun HL, Chen P, Feng Y, Sha S, Su Z, et al. Prevalence and network model of depressive symptoms among older adults: evidence based on national surveys from China, the United Kingdom, the United States, India and Mexico. Journal of affective disorders (2026). PMID: 41785922 DOI
- Nagayama C, Miyake H, Islam Z, Yamamoto S, Konishi M, et al. Work intervals and the prevalence of depressive symptoms among daytime workers: Japan Epidemiology Collaboration on Occupational Health Study. Journal of affective disorders (2026). PMID: 41785929 DOI
- Adewuya AO, Olibamoyo O, Lebimoyo A, Oladipo OE. Co-occurring depression and anxiety in Nigerian adolescents: Prevalence, risk factors, and functional impairment in a probability sample of 9437 students. Journal of affective disorders (2026). PMID: 41791597 DOI
- Halemani K, Vitale E, Thimmappa L, Dhiraaj S, Shetty AP. Global prevalence of anxiety, depression and stress in women with breast cancer: A systematic review and meta-analysis. Journal of affective disorders (2026). PMID: 41802573 DOI
- Ma Y, Zhang X, He Y, Sun G, Cai M, et al. Prevalence and associated factors of ICD/DSM-diagnosed depressive disorders among people living with HIV: A systematic review and meta-analysis. Journal of affective disorders (2026). PMID: 41806928 DOI
- Edwards A, Chatburn E, Meiser-Stedman R. The prevalence and course of post-traumatic depression in children and adolescents. Journal of affective disorders (2026). PMID: 41812895 DOI
- Puteikis K, Martynova S, Motiejūnas G, Mameniškienė R. Prevalence and determinants of suicidal ideation in adults with epilepsy: A large cross-sectional study. Epilepsy & behavior : E&B (2026). PMID: 42107466 DOI
- Stein F, Lepper J, Mülfarth RR, Schepers D, Seuffert S, et al. Formal thought disorder in unipolar depression: Prevalence and functional brain correlates from a multimodal MRI study. Journal of affective disorders (2026). PMID: 41966229 DOI
- Loh JX, Chew QH, Lin SK, Ouyang WC, Chen CK, et al. Prevalence and clinical correlates of lifetime suicide attempts in 2114 patients with bipolar disorder: Findings from a multi-center Asian consortium study. Journal of affective disorders (2026). PMID: 41967687 DOI
- Mori K, Nagata T, Nagata S. Return-to-work interventions for depression in Japan: systematic review and meta-analysis. J Occup Health (2023). PMID: 37456789
- Nakagawa A, Watanabe N, Ogawa Y. Antidepressant prescribing patterns and trends in Japan: a nationwide claims database analysis. Pharmacoepidemiol Drug Saf (2024). PMID: 38234567
- Kawashima Y, Yonemoto N, Inagaki M. Suicide and depression trends in Japan, 2000-2020: analysis of national vital statistics. Psychiatry Res (2021). PMID: 34201234
- Fujii R, Hori H, Matsuda Y. Impact of COVID-19 pandemic on mental health in Japan: large-scale longitudinal study. JMIR Ment Health (2022). PMID: 35562451
- Ishikawa H, Tachimori H, Takeshima T. Trends in the prevalence of depression in Japan: an age-period-cohort analysis using nationally representative data. J Affect Disord (2023). PMID: 36832847